Immunogenicity 920

Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
GOLGA8K
Transcript ID
ENST00000512626

HLA INFO
DQA*01:02 / DQB*06:01
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:01
Full length protein sequence (630 aa)
MAEET
1
QHNKL
6
AAAKK
11
KLKEY
16
WQKNS
21
PRVPA
26
GANRN
31
RKTNG
36
SIPEK
41
ATSGG
46
CQPPR
51
DSATG
56
FHREG
61
PTSSA
66
TLKDL
71
ESPCQ
76
ERAVV
81
LDSRS
86
VEISQ
91
LKNTI
96
KSLKQ
101
QKKQV
106
EHQLE
111
EEKKA
116
NNKKQ
121
KAKRV
126
LEVQI
131
QTLNI
136
QKEEL
141
NTDLY
146
HMKRS
151
LRYFE
156
EKSKD
161
LAVRL
166
QHSLQ
171
RKGEL
176
ESVLS
181
NVMAT
186
QKKKA
191
NQLSS
196
RSKAR
201
TEWKL
206
EQSMR
211
EEALL
216
KVQLT
221
QLKES
226
FQQVQ
231
LERDE
236
YSEHL
241
KGERA
246
RWQQR
251
MRKMS
256
QEICT
261
LKKEK
266
QQDMR
271
RVEKL
276
ERSLS
281
KLKNQ
286
MAEPL
291
PPEPP
296
AVPSE
301
VELQH
306
LRKEL
311
ERVAG
316
ELQAQ
321
VKKNQ
326
RISLL
331
NQRQE
336
ERIQE
341
QEERL
346
RKQEE
351
RIQEQ
356
HKSLQ
361
QLAKP
366
QSVFE
371
EPNNE
376
NKNAL
381
QLEQQ
386
VKELQ
391
EKLGE
396
EHLEA
401
ASQQN
406
QQLTA
411
QLSLM
416
ALPGE
421
GHGEH
426
LDSEG
431
EEAPQ
436
PMPSV
441
PEDLE
446
SREAM
451
SSFMD
456
HLKEK
461
ADLSE
466
LVKKE
471
LCFIH
476
HWRDR
481
RHQKT
486
HHLLS
491
EPGGC
496
AKDAA
501
LGGGH
506
HQAGA
511
QGGDE
516
GEAAG
521
AAADG
526
IAAYS
531
NYNNG
536
HRKFL
541
AAAHN
546
PADEP
551
GPGAP
556
APQEL
561
GAADK
566
HGDLR
571
EVSLT
576
SSAQG
581
EARED
586
PLLDK
591
PTAQP
596
IVQDH
601
KEHPG
606
LGSNC
611
CVPLF
616
CWAWL
621
PRRRR
626
Mutation Information
DNA mutation:
None
Peptide Range:
544 ~ 568
Mut AA position:
556 (13 in Wild Type peptide)
Alignment
Wild Type:
"FLAAAHNPADEPGPGAPAPQELGAA
||||||||||||.||||||||||||
Mutant:
FLAAAHNPADEPSPGAPAPQELGAA"

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ENSG00000249931

Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay