Immunogenicity 958

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
CDKN2AIP
Transcript ID
ENST00000438828
HLA INFO
DQA*02:01 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*02:01 DQB*02:02
sequence
Full length protein sequence (725 aa)
MEQSN
1
DSLRV
6
NHNDG
11
EESKT
16
SAQVF
21
EHLIC
26
MDSRD
31
SSFGQ
36
NDSPT
41
VLPIT
46
TREAN
51
NSLIS
56
QNIPG
61
PLTQT
66
QTLSA
71
EQFHL
76
VDQNG
81
QAIQY
86
ELQSL
91
GESNA
96
QMMIV
101
ASPTE
106
NGQVL
111
RVIPP
116
TQTGM
121
AQVII
126
PQGQL
131
VDVNS
136
PRDVP
141
EEKPS
146
NRNLP
151
TVRVD
156
TLADN
161
TSNYI
166
LHPQT
171
SFPLP
176
KKSVT
181
GMLEE
186
PLLGP
191
LQPLS
196
SNTPI
201
WACRL
206
RSCEK
211
IGDSY
216
RGYCV
221
SETEL
226
ESVLT
231
FHKQQ
236
TQSVW
241
GTRQS
246
PSPAK
251
PATRL
256
MWKSQ
261
YVPYD
266
GIPFV
271
NAGSR
276
AVVME
281
CQYGP
286
RRKGF
291
QLKKV
296
SEQES
301
RSCQL
306
YKATC
311
PARIY
316
IKKVQ
321
KFPEY
326
RVPTD
331
PKIDK
336
KIIRM
341
EQEKA
346
FNMLK
351
KNLVD
356
AGGVL
361
RWYVQ
366
LPTQQ
371
AHQYH
376
ELETP
381
CLTLS
386
PSPFP
391
VSSLE
396
EEETA
401
VRDEN
406
CALPS
411
RLHPQ
416
VAHKI
421
QELVS
426
QGIEQ
431
VYAVR
436
KQLRK
441
FVERE
446
LFKPD
451
EVPER
456
HNLSF
461
FPTVN
466
DIKNH
471
IHEVQ
476
KSLRN
481
GDTVY
486
NSEII
491
PATLQ
496
WTTDS
501
GNILK
506
ETMTV
511
TFAEG
516
NSPGE
521
SITTK
526
VETNQ
531
TRGSL
536
SPEPT
541
HLLSS
546
LSSFQ
551
PKIFT
556
QLQGL
561
QLQPR
566
YTSPD
571
ESPAV
576
VSVNN
581
QPSSS
586
PSGLL
591
DTIGS
596
AVMNN
601
NSLLL
606
GQSHS
611
LQRDT
616
CLTQN
621
NSTAS
626
TMGNL
631
PEPDQ
636
NLVAM
641
DELVE
646
VGDVE
651
DTGNL
656
EGTVH
661
RILLG
666
DVQTI
671
PIQII
676
DNHSA
681
LIEEN
686
PESTI
691
SVSQV
696
KQEPK
701
EPALS
706
MEAKK
711
TVDYK
716
KLSAT
721
Mutation Information
DNA mutation:
None
Peptide Range:
259 ~ 283
Mut AA position:
271 (13 in Wild Type peptide)
Alignment
Wild Type:
"RLMWKSQYVPYDGIPFVNAGSRAVV
||||||||||||.||||||||||||
Mutant:
RLMWKSQYVPYDEIPFVNAGSRAVV"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) CARF

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay