Immunogenicity 966

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
DZIP1L
Transcript ID
ENST00000327532
HLA INFO
DQA*05:01 / DQB*06:03
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*05:01 DQB*06:03
sequence
Full length protein sequence (767 aa)
MQSPA
1
ATAEG
6
LSGPL
11
FGAYT
16
FPTFK
21
FQPRH
26
DSMDW
31
RRIST
36
LDVDR
41
VAREL
46
DVATL
51
QENIA
56
GITFC
61
NLDRE
66
VCSRC
71
GQPVD
76
PALLK
81
VLRLA
86
QLIIE
91
YLLHC
96
QDCLS
101
ASVAQ
106
LEARL
111
QTSLG
116
QQQRG
121
QQELG
126
RQADE
131
LKGVR
136
EESRR
141
RRKMI
146
STLQQ
151
LLMQT
156
GTHSY
161
HTCHL
166
CDKTF
171
MNATF
176
LRGHI
181
QRRHA
186
GVAEG
191
GKQKK
196
QEQPV
201
EEVLE
206
ELRAK
211
LKWTQ
216
GELEA
221
QREAE
226
RQRQL
231
QEAEL
236
IHQRE
241
IEAKK
246
EFDKW
251
KEQEW
256
TKLYG
261
EIDKL
266
KKLFW
271
DEFKN
276
VAKQN
281
STLEE
286
KLRAL
291
QSHSV
296
MESKL
301
GSLRD
306
EESEE
311
WLRQA
316
RELQA
321
LREKT
326
EIQKT
331
EWKRK
336
VKELH
341
EEHMA
346
EKKEL
351
QEENQ
356
RLQAS
361
LSQDQ
366
KKAAA
371
QSQCQ
376
ISTLR
381
AQLQE
386
QARII
391
ASQEE
396
MIQSL
401
SLRKV
406
EGIHK
411
VPKAV
416
DTEED
421
SPEEE
426
MEDSQ
431
DEQHK
436
VLAAL
441
RRNPT
446
LLKHF
451
RPILE
456
DTLEE
461
KLESM
466
GIRKD
471
AKGIS
476
IQTLR
481
HLESL
486
LRVQR
491
EQKAR
496
KFSEF
501
LSLRG
506
KLVKE
511
VTSRA
516
KERQE
521
NGAVV
526
SQPDG
531
QPSVK
536
SQQST
541
LVTRE
546
AQPKT
551
RTLQV
556
ALPST
561
PAEPP
566
PPTRQ
571
SHGSH
576
GSSLT
581
QVSAP
586
APRPG
591
LHGPS
596
STPPS
601
SGPGM
606
STPPF
611
SSEED
616
SEGDR
621
VQRVS
626
LQPPK
631
VPSRM
636
VPRPK
641
DDWDW
646
SDTET
651
SEENA
656
QPPGQ
661
GSGTL
666
VQSMV
671
KNLEK
676
QLEAP
681
AKKPA
686
GGVSL
691
FFMPN
696
AGPQR
701
AATPG
706
RKPQL
711
SEDES
716
DLEIS
721
SLEDL
726
PLDLD
731
QREKP
736
KPLSR
741
SKLPE
746
KFGTG
751
PQSSG
756
QPRVP
761
AW
766
Mutation Information
DNA mutation:
None
Peptide Range:
25 ~ 49
Mut AA position:
37 (13 in Wild Type peptide)
Alignment
Wild Type:
"KFQPRHDSMDWRRISTLDVDRVARE
||||||||||||.||||||||||||
Mutant:
KFQPRHDSMDWRCISTLDVDRVARE"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) DZIP1L

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay