Immunogenicity 97
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
CACNA1D
Transcript ID
uc003dgy.5
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (2146 aa)
MMMMM
1
MMKKM
6
QHQRQ
11
QQADH
16
ANEAN
21
YARGT
26
RLPLS
31
GEGPT
36
SQPNS
41
SKQTV
46
LSWQA
51
AIDAA
56
RQAKA
61
AQTMS
66
TSAPP
71
PVGSL
76
SQRKR
81
QQYAK
86
SKKQG
91
NSSNS
96
RPARA
101
LFCLS
106
LNNPI
111
RRACI
116
SIVEW
121
KPFDI
126
FILLA
131
IFANC
136
VALAI
141
YIPFP
146
EDDSN
151
STNHN
156
LEKVE
161
YAFLI
166
IFTVE
171
TFLKI
176
IAYGL
181
LLHPN
186
AYVRN
191
GWNLL
196
DFVIV
201
IVGLF
206
SVILE
211
QLTKE
216
TEGGN
221
HSSGK
226
SGGFD
231
VKALR
236
AFRVL
241
RPLRL
246
VSGVP
251
SLQVV
256
LNSII
261
KAMVP
266
LLHIA
271
LLVLF
276
VIIIY
281
AIIGL
286
ELFIG
291
KMHKT
296
CFFAD
301
SDIVA
306
EEDPA
311
PCAFS
316
GNGRQ
321
CTANG
326
TECRS
331
GWVGP
336
NGGIT
341
NFDNF
346
AFAML
351
TVFQC
356
ITMEG
361
WTDVL
366
YWVND
371
AIGWE
376
WPWVY
381
FVSLI
386
ILGSF
391
FVLNL
396
VLGVL
401
SGEFS
406
KEREK
411
AKARG
416
DFQKL
421
REKQQ
426
LEEDL
431
KGYLD
436
WITQA
441
EDIDP
446
ENEEE
451
GGEEG
456
KRNTS
461
MPTSE
466
TESVN
471
TENVS
476
GEGEN
481
RGCCG
486
SLCQA
491
ISKSK
496
LSRRW
501
RRWNR
506
FNRRR
511
CRAAV
516
KSVTF
521
YWLVI
526
VLVFL
531
NTLTI
536
SSEHY
541
NQPDW
546
LTQIQ
551
DIANK
556
VLLAL
561
FTCEM
566
LVKMY
571
SLGLQ
576
AYFVS
581
LFNRF
586
DCFVV
591
CGGIT
596
ETILV
601
ELEIM
606
SPLGI
611
SVFRC
616
VRLLR
621
IFKVT
626
RHWTS
631
LSNLV
636
ASLLN
641
SMKSI
646
ASLLL
651
LLFLF
656
IIIFS
661
LLGMQ
666
LFGGK
671
FNFDE
676
TQTKR
681
STFDN
686
FPQAL
691
LTVFQ
696
ILTGE
701
DWNAV
706
MYDGI
711
MAYGG
716
PSSSG
721
MIVCI
726
YFIIL
731
FICGN
736
YILLN
741
VFLAI
746
AVDNL
751
ADAES
756
LNTAQ
761
KEEAE
766
EKERK
771
KIARK
776
ESLEN
781
KKNNK
786
PEVNQ
791
IANSD
796
NKVTI
801
DDYRE
806
EDEDK
811
DPYPP
816
CDVPV
821
GEEEE
826
EEEED
831
EPEVP
836
AGPRP
841
RRISE
846
LNMKE
851
KIAPI
856
PEGSA
861
FFILS
866
KTNPI
871
RVGCH
876
KLINH
881
HIFTN
886
LILVF
891
IMLSS
896
AALAA
901
EDPIR
906
SHSFR
911
NTILG
916
YFDYA
921
FTAIF
926
TVEIL
931
LKMTT
936
FGAFL
941
HKGAF
946
CRNYF
951
NLLDM
956
LVVGV
961
SLVSF
966
GIQSS
971
AISVV
976
KILRV
981
LRVLR
986
PLRAI
991
NRAKG
996
LKHVV
1001
QCVFV
1006
AIRTI
1011
GNIMI
1016
VTTLL
1021
QFMFA
1026
CIGVQ
1031
LFKGK
1036
FYRCT
1041
DEAKS
1046
NPEEC
1051
RGLFI
1056
LYKDG
1061
DVDSP
1066
VVRER
1071
IWQNS
1076
DFNFD
1081
NVLSA
1086
MMALF
1091
TVSTF
1096
EGWPA
1101
LLYKA
1106
IDSNG
1111
ENIGP
1116
IYNHR
1121
VEISI
1126
FFIIY
1131
IIIVA
1136
FFMMN
1141
IFVGF
1146
VIVTF
1151
QEQGE
1156
KEYKN
1161
CELDK
1166
NQRQC
1171
VEYAL
1176
KARPL
1181
RRYIP
1186
KNPYQ
1191
YKFWY
1196
VVNSS
1201
PFEYM
1206
MFVLI
1211
MLNTL
1216
CLAMQ
1221
HYEQS
1226
KMFND
1231
AMDIL
1236
NMVFT
1241
GVFTV
1246
EMVLK
1251
VIAFK
1256
PKGYF
1261
SDAWN
1266
TFDSL
1271
IVIGS
1276
IIDVA
1281
LSEAD
1286
NSEES
1291
NRISI
1296
TFFRL
1301
FRVMR
1306
LVKLL
1311
SRGEG
1316
IRTLL
1321
WTFIK
1326
SFQAL
1331
PYVAL
1336
LIAML
1341
FFIYA
1346
VIGMQ
1351
MFGKV
1356
AMRDN
1361
NQINR
1366
NNNFQ
1371
TFPQA
1376
VLLLF
1381
RCATG
1386
EAWQE
1391
IMLAC
1396
LPGKL
1401
CDPES
1406
DYNPG
1411
EEYTC
1416
GSNFA
1421
IVYFI
1426
SFYML
1431
CAFLI
1436
INLFV
1441
AVIMD
1446
NFDYL
1451
TRDWS
1456
ILGPH
1461
HLDEF
1466
KRIWS
1471
EYDPE
1476
AKGRI
1481
KHLDV
1486
VTLLR
1491
RIQPP
1496
LGFGK
1501
LCPHR
1506
VACKR
1511
LVAMN
1516
MPLNS
1521
DGTVM
1526
FNATL
1531
FALVR
1536
TALKI
1541
KTEGN
1546
LEQAN
1551
EELRA
1556
VIKKI
1561
WKKTS
1566
MKLLD
1571
QVVPP
1576
AGDDE
1581
VTVGK
1586
FYATF
1591
LIQDY
1596
FRKFK
1601
KRKEQ
1606
GLVGK
1611
YPAKN
1616
TTIAL
1621
QAGLR
1626
TLHDI
1631
GPEIR
1636
RAISC
1641
DLQDD
1646
EPEET
1651
KREEE
1656
DDVFK
1661
RNGAL
1666
LGNHV
1671
NHVNS
1676
DRRDS
1681
LQQTN
1686
TTHRP
1691
LHVQR
1696
PSIPP
1701
ASDTE
1706
KPLFP
1711
PAGNS
1716
VCHNH
1721
HNHNS
1726
IGKQV
1731
PTSTN
1736
ANLNN
1741
ANMSK
1746
AAHGK
1751
RPSIG
1756
NLEHV
1761
SENGH
1766
HSSHK
1771
HDREP
1776
QRRSS
1781
VKRTR
1786
YYETY
1791
IRSDS
1796
GDEQL
1801
PTICR
1806
EDPEI
1811
HGYFR
1816
DPHCL
1821
GEQEY
1826
FSSEE
1831
CYEDD
1836
SSPTW
1841
SRQNY
1846
GYYSR
1851
YPGRN
1856
IDSER
1861
PRGYH
1866
HPQGF
1871
LEDDD
1876
SPVCY
1881
DSRRS
1886
PRRRL
1891
LPPTP
1896
ASHRR
1901
SSFNF
1906
ECLRR
1911
QSSQE
1916
EVPSS
1921
PIFPH
1926
RTALP
1931
LHLMQ
1936
QQIMA
1941
VAGLD
1946
SSKAQ
1951
KYSPS
1956
HSTRS
1961
WATPP
1966
ATPPY
1971
RDWTP
1976
CYTPL
1981
IQVEQ
1986
SEALD
1991
QVNGS
1996
LPSLH
2001
RSSWY
2006
TDEPD
2011
ISYRT
2016
FTPAS
2021
LTVPS
2026
SFRNK
2031
NSDKQ
2036
RSADS
2041
LVEAV
2046
LISEG
2051
LGRYA
2056
RDPKF
2061
VSATK
2066
HEIAD
2071
ACDLT
2076
IDEME
2081
SAAST
2086
LLNGN
2091
VRPRA
2096
NGDVG
2101
PLSHR
2106
QDYEL
2111
QDFGP
2116
GYSDE
2121
EPDPG
2126
RDEED
2131
LADEM
2136
ICITT
2141
L
2146
Mutation Information
DNA mutation:
c.G67A
Peptide Range:
11 ~ 35
Mut AA position:
23 (13 in Wild Type peptide)
Alignment
Wild Type:
"QHQRQQQADHANEANYARGTRLPLS
||||||||||||.||||||||||||
Mutant:
QHQRQQQADHANKANYARGTRLPLS"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) CACNA1D
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
QHQRQQQADHANKANYARGTRLPLS
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT