Immunogenicity 9741
Sample ID
3812
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
TTC28
Transcript ID
ENST00000397906
HLA INFO
DRB*13:01
TCR INFO
No TCR info found!
Full length protein sequence (2481 aa)
MEQSP
1
PPAPE
6
PTQGP
11
TPARS
16
RRRRE
21
PESPP
26
ASAPI
31
PLFGA
36
DTIGQ
41
RSPDG
46
PVLSK
51
AEFVE
56
KVRQS
61
NQACH
66
DGDFH
71
TAIVL
76
YNEAL
81
AVDPQ
86
NCILY
91
SNRSA
96
AYMKI
101
QQYDK
106
ALDDA
111
IKARL
116
LNPKW
121
PKAYF
126
RQGVA
131
LQYLG
136
RHADA
141
LAAFA
146
SGLAQ
151
DPKSL
156
QLLVG
161
MVEAA
166
MKSPM
171
RDSLE
176
PTYQQ
181
LQKMK
186
LDKSP
191
FVVVS
196
VVGQE
201
LLTAG
206
HHGAS
211
VVVLE
216
AALKI
221
GTCSL
226
KLRGS
231
VFSAL
236
SSAYW
241
SLGNT
246
EKSTG
251
YMQQD
256
LDVAK
261
TLGDQ
266
TGECR
271
AHGNL
276
GSAFF
281
SKGNY
286
REALT
291
NHRHQ
296
LVLAM
301
KLKDR
306
EAASS
311
ALSSL
316
GHVYT
321
AIGDY
326
PNALA
331
SHKQC
336
VLLAK
341
QSKDE
346
LSEAR
351
ELGNM
356
GAVYI
361
AMGDF
366
ENAVQ
371
CHEQH
376
LKIAK
381
DLGNK
386
REEAR
391
AYSNL
396
GSAYH
401
YRRNF
406
DKAMS
411
YHNYV
416
LELAQ
421
ELMEK
426
AIEMR
431
AYAGL
436
GHAAR
441
CMQDL
446
ERAKQ
451
YHEQQ
456
LGIAE
461
DLKDR
466
AAEGR
471
ASSNL
476
GIIHQ
481
MKGDY
486
DTALK
491
LHKTH
496
LCIAQ
501
ELSDY
506
AAQGR
511
AYGNM
516
GNAYN
521
ALGMY
526
DQAVK
531
YHRQE
536
LQISM
541
EVNDR
546
ASQAS
551
THGNL
556
AVAYQ
561
ALGAH
566
DRALQ
571
HYQNH
576
LNIAR
581
ELRDI
586
QSEAR
591
ALSNL
596
GNFHC
601
SRGEY
606
VQAAP
611
YYEQY
616
LRLAP
621
DLQDM
626
EGEGK
631
VCHNL
636
GYAHY
641
CLGNY
646
QEAVK
651
YYEQD
656
LALAK
661
DLHDK
666
LSQAK
671
AYCNL
676
GLAFK
681
ALLNF
686
SKAEE
691
CQKYL
696
LSLAQ
701
SLNNS
706
QAKFR
711
ALGNL
716
GDIFI
721
CKKDI
726
NGAIK
731
FYEQQ
736
LGLAH
741
QVKDR
746
RLEAS
751
AYAAL
756
GTAYR
761
MIQKY
766
DKALG
771
YHTQE
776
LEVYQ
781
ELSDL
786
PGECR
791
AHGHL
796
AAVYM
801
ALGKY
806
TMAFK
811
CYEEQ
816
LDLGQ
821
KLKDP
826
SLEAQ
831
VYGNM
836
GITKM
841
NMNVM
846
EEAIG
851
YFEQQ
856
LAMLQ
861
QLSGN
866
ESVLD
871
RGRAY
876
GNLGD
881
CYEAL
886
GDYEE
891
AIKYY
896
EQYLS
901
VAQSL
906
NRMQD
911
QAKAY
916
RGLGN
921
GHRAM
926
GSLQQ
931
ALVCF
936
EKRLV
941
VAHEL
946
GEAFN
951
KAQAY
956
GELGS
961
LHSQL
966
GNYEQ
971
AISCL
976
ERQLN
981
IARDM
986
KDRAL
991
ESDAA
996
CGLGG
1001
VYQQM
1006
GEYDT
1011
ALQYH
1016
QLDLQ
1021
IAEET
1026
NNPTC
1031
QGRAY
1036
GNLGL
1041
TYESL
1046
GTFER
1051
AVVYQ
1056
EQHLS
1061
IAAQM
1066
NDLAA
1071
KTVSY
1076
SSLGR
1081
THHAL
1086
QNYSQ
1091
AVMYL
1096
QEGLR
1101
LAEQL
1106
GRRED
1111
EAKIR
1116
HGLGL
1121
SLWAS
1126
GNLEE
1131
AQHQL
1136
YRASA
1141
LFETI
1146
RHEAQ
1151
LSTDY
1156
KLSLF
1161
DLQTS
1166
SYQAL
1171
QRVLV
1176
SLGHH
1181
DEALA
1186
VAERG
1191
RTRAF
1196
ADLLV
1201
ERQTG
1206
QQDSD
1211
PYSPV
1216
TIDQI
1221
LEMVN
1226
GQRGL
1231
VLYYS
1236
LAAGY
1241
LYSWL
1246
LAPGA
1251
GIVKF
1256
HEHYL
1261
GENTV
1266
ENSSD
1271
FQASS
1276
SVTLP
1281
TATGS
1286
ALEQH
1291
IASVR
1296
EALGV
1301
ESHYS
1306
RACAS
1311
SETES
1316
EAGDI
1321
MDQQF
1326
EEMNN
1331
KLNSV
1336
TDPTG
1341
FLRMV
1346
RRNNL
1351
FNRSC
1356
QSMTS
1361
LFSNT
1366
VSPTQ
1371
DGTSS
1376
LPRRQ
1381
SSFAK
1386
PPLRA
1391
LYDLL
1396
IAPME
1401
GGLMH
1406
SSGPV
1411
GRHRQ
1416
LILVL
1421
EGELY
1426
LIPFA
1431
LLKGS
1436
SSNEY
1441
LYERF
1446
GLLAV
1451
PSIRS
1456
LSVQS
1461
KSHLR
1466
KNPPT
1471
YSSST
1476
SMAAV
1481
IGNPK
1486
LPSAV
1491
MDRWL
1496
WGPMP
1501
SAEEE
1506
AYMVS
1511
ELLGC
1516
QPLVG
1521
SVATK
1526
ERVMS
1531
ALTQA
1536
ECVHF
1541
ATHIS
1546
WKLSA
1551
LVLTP
1556
SMDGN
1561
PASSK
1566
SSFGH
1571
PYTIP
1576
ESLRV
1581
QDDAS
1586
DGESI
1591
SDCPP
1596
LQELL
1601
LTAAD
1606
VLDLQ
1611
LPVKL
1616
VVLGS
1621
SQESN
1626
SKVTA
1631
DGVIA
1636
LTRAF
1641
LAAGA
1646
QCVLV
1651
SLWPV
1656
PVAAS
1661
KMFIH
1666
AFYSS
1671
LLNGL
1676
KASAA
1681
LGEAM
1686
KVVQS
1691
SKAFS
1696
HPSNW
1701
AGFML
1706
IGSDV
1711
KLNSP
1716
SSLIG
1721
QALTE
1726
ILQHP
1731
ERARD
1736
ALRVL
1741
LHLVE
1746
KSLQR
1751
IQNGQ
1756
RNAMY
1761
TSQQS
1766
VENKV
1771
GGIPG
1776
WQALL
1781
TAVGF
1786
RLDPP
1791
TSGLP
1796
AAVFF
1801
PTSDP
1806
GDRLQ
1811
QCSST
1816
LQSLL
1821
GLPNP
1826
ALQAL
1831
CKLIT
1836
ASETG
1841
EQLIS
1846
RAVKN
1851
MVGML
1856
HQVLV
1861
QLQAG
1866
EKEQD
1871
LASAP
1876
IQVSI
1881
SVQLW
1886
RLPGC
1891
HEFLA
1896
ALGFD
1901
LCEVG
1906
QEEVI
1911
LKTGK
1916
QANRR
1921
TVHFA
1926
LQSLL
1931
SLFDS
1936
TELPK
1941
RLSLD
1946
SSSSL
1951
ESLAS
1956
AQSVS
1961
NALPL
1966
GYQQP
1971
PFSPT
1976
GADSI
1981
ASDAI
1986
SVYSL
1991
SSIAS
1996
SMSFV
2001
SKPEG
2006
GSEGG
2011
GPGGR
2016
QDHDR
2021
SKNAY
2026
LQRST
2031
LPRSQ
2036
LPPQT
2041
RPAGN
2046
KDEEE
2051
YEGFS
2056
IISNE
2061
PLATY
2066
QENRN
2071
TCFSP
2076
DHKQP
2081
QPGTA
2086
GGMRV
2091
SVSSK
2096
GSIST
2101
PNSPV
2106
KMTLI
2111
PSPNS
2116
PFQKV
2121
GKLAS
2126
SDTGE
2131
SDQSS
2136
TETDS
2141
TVKSQ
2146
EESNP
2151
KLDPQ
2156
ELAQK
2161
ILEET
2166
QSHLI
2171
AVERL
2176
QRSGG
2181
QVSKS
2186
NNPED
2191
GVQAP
2196
SSTAV
2201
FRASE
2206
TSAFS
2211
RPVLS
2216
HQKSQ
2221
PSPVT
2226
VKPKP
2231
PARSS
2236
SLPKV
2241
SSGYS
2246
SPTTS
2251
EMSIK
2256
DSPSQ
2261
HSGRP
2266
SPGCD
2271
SQTSQ
2276
LDQPL
2281
FKLKY
2286
PSSPY
2291
SAHIS
2296
KSPRN
2301
MSPSS
2306
GHQSP
2311
AGSAP
2316
SPALS
2321
YSSAG
2326
SARSS
2331
PADAP
2336
DIDKL
2341
KMAAI
2346
DEKVQ
2351
AVHNL
2356
KMFWQ
2361
STPQH
2366
STGPM
2371
KIFRG
2376
APGTM
2381
TSKRD
2386
VLSLL
2391
NLSPR
2396
HNKKE
2401
EGVDK
2406
LELKE
2411
LSLQQ
2416
HDGAP
2421
PKAPP
2426
NGHWR
2431
TETTS
2436
LGSLP
2441
LPAGP
2446
PATAP
2451
ARPLR
2456
LPSGN
2461
GYKFL
2466
SPGRF
2471
FPSSK
2476
C
2481
Mutation Information
DNA mutation:
None
Peptide Range:
1845 ~ 1869
Mut AA position:
1857 (13 in Wild Type peptide)
Alignment
Wild Type:
"GEQLISRAVKNMVGMLHQVLVQLQA
||||||||||||.||||||||||||
Mutant:
GEQLISRAVKNMFGMLHQVLVQLQA"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) TTC28
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
None
Assay
IFNg ELISPOT assay