Immunogenicity 9940

summary
Sample ID
3812
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
LRCH1
Transcript ID
ENST00000311191
HLA INFO
A*68:01
TCR INFO

No TCR info found!

T cell Tumor cell A*68:01
sequence
Full length protein sequence (696 aa)
MATPG
1
SEPQP
6
FVPAL
11
SVATL
16
HPLHH
21
PHHHH
26
HHHQH
31
HGGTG
36
APGGA
41
GGGGG
46
GSGGF
51
NLPLN
56
RGLER
61
ALEEA
66
ANSGG
71
LNLSA
76
RKLKE
81
FPRTA
86
APGHD
91
LSDTV
96
QADLS
101
KNRLV
106
EVPME
111
LCHFV
116
SLEIL
121
NLYHN
126
CIRVI
131
PEAIV
136
NLQML
141
TYLNL
146
SRNQL
151
SALPA
156
CLCGL
161
PLKVL
166
IASNN
171
KLGSL
176
PEEIG
181
QLKQL
186
MELDV
191
SCNEI
196
TALPQ
201
QIGQL
206
KSLRE
211
LNVRR
216
NYLKV
221
LPQEL
226
VDLSL
231
VKFDF
236
SCNKV
241
LVIPI
246
CFREM
251
KQLQV
256
LLLEN
261
NPLQS
266
PPAQI
271
CTKGK
276
VHIFK
281
YLSIQ
286
ACQIK
291
TADSL
296
YLHTM
301
ERPHL
306
HQHVE
311
DGKKD
316
SDSGV
321
GSDNG
326
DKRLS
331
ATEPS
336
DEDTV
341
SLNVP
346
MSNIM
351
EEEQI
356
IKEDS
361
CHRLS
366
PVKGE
371
FHQEF
376
QPEPS
381
LLGDS
386
TNSGE
391
ERDQF
396
TDRAD
401
GLHSE
406
FMNYK
411
ARAED
416
CEELL
421
RIEED
426
VHWQT
431
EGIIS
436
SSKDQ
441
DMDIA
446
MIEQL
451
REAVD
456
LLQDP
461
NGLST
466
DITER
471
SVLNL
476
YPMGS
481
AEALE
486
LQDSA
491
LNGQI
496
QLETS
501
PVCEV
506
QSDLT
511
LQSNG
516
SQYSP
521
NEIRE
526
NSPAV
531
SPTTN
536
STAPF
541
GLKPR
546
SVFLR
551
PQRNL
556
ESIDP
561
QFTIR
566
RKMEQ
571
MREEK
576
ELVEQ
581
LRESI
586
EMRLK
591
VSLHE
596
DLGAA
601
LMDGV
606
VLCHL
611
VNHIR
616
PRSVA
621
SIHVP
626
SPAVP
631
KLSMA
636
KCRRN
641
VENFL
646
EACRK
651
LGVPE
656
EKLCL
661
PHHIL
666
EEKGL
671
VKVGI
676
TIQAL
681
LDITV
686
TKALF
691
T
696
Mutation Information
DNA mutation:
None
Peptide Range:
534 ~ 558
Mut AA position:
546 (13 in Wild Type peptide)
Alignment
Wild Type:
"AVSPTTNSTAPFGLKPRSVFLRPQR
||||||||||||.||||||||||||
Mutant:
AVSPTTNSTAPFVLKPRSVFLRPQR"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) LRCH1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

None

Assay

IFNg ELISPOT assay