Immunogenicity 998

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
FBLN2
Transcript ID
ENST00000295760
HLA INFO
C*08:02
TCR INFO

No TCR info found!

T cell Tumor cell C*08:02
sequence
Full length protein sequence (1184 aa)
MVLLW
1
EPAGA
6
WLALG
11
LALAL
16
GPSVA
21
AAAPR
26
QDCTG
31
VECPP
36
LENCI
41
EEALE
46
PGACC
51
ATCVQ
56
QGCAC
61
EGYQY
66
YDCLQ
71
GGFVR
76
GRVPA
81
GQSYF
86
VDFGS
91
TECSC
96
PPGGG
101
KISCQ
106
FMLCP
111
ELPPN
116
CIEAV
121
VVADS
126
CPQCG
131
QVGCV
136
HAGHK
141
YAAGH
146
TVHLP
151
PCRAC
156
HCPDA
161
GGELI
166
CYQLP
171
GCHGN
176
FSDAE
181
EGDPE
186
RHYED
191
PYSYD
196
QEVAE
201
VEAAT
206
ALGGE
211
VQAGA
216
VQAGA
221
GGPPA
226
ALGGG
231
SQPLS
236
TIQAP
241
PWPAV
246
LPRPT
251
AAAAL
256
GPPAP
261
VQAKA
266
RRVTE
271
DSEEE
276
EEEEE
281
EREEM
286
AVTEQ
291
LAAGG
296
HRGLD
301
GLPTT
306
APAGP
311
SLPIQ
316
EERAE
321
AGARA
326
EAGAR
331
PEENL
336
ILDAQ
341
ATSRS
346
TGPEG
351
VTHAP
356
SLGKA
361
ALVPT
366
QAVPG
371
SPRDP
376
VKPSP
381
HNILS
386
TSLPD
391
AAWIP
396
PTREV
401
PRKPQ
406
VLPHS
411
HVEED
416
TDPNS
421
VHSIP
426
RSSPE
431
GSTKD
436
LIETC
441
CAAGQ
446
QWAID
451
NDECL
456
EIPES
461
GTEDN
466
VCRTA
471
QRHCC
476
VSYLQ
481
EKSCM
486
AGVLG
491
AKEGE
496
TCGAE
501
DNDSC
506
GISLY
511
KQCCD
516
CCGLG
521
LRVRA
526
EGQSC
531
ESNPN
536
LGYPC
541
NHVML
546
SCCEG
551
EEPLI
556
VPEVR
561
RPPEP
566
AAAPR
571
RVSEA
576
EMAGR
581
EALSL
586
GTEAE
591
LPNSL
596
PGDDQ
601
DECLL
606
LPGEL
611
CQHLC
616
INTVG
621
SYHCA
626
CFPGF
631
SLQDD
636
GRTCR
641
PEGHP
646
PQPEA
651
PQEPA
656
LKSEF
661
SQVAS
666
NTIPL
671
PLPQP
676
NTCKD
681
NGPCK
686
QVCST
691
VGGSA
696
ICSCF
701
PGYAI
706
MADGV
711
SCEDI
716
NECVT
721
DLHTC
726
SRGEH
731
CVNTL
736
GSFHC
741
YKALT
746
CEPGY
751
ALKDG
756
ECEDV
761
DECAM
766
GTHTC
771
QPGFL
776
CQNTK
781
GSFYC
786
QARQR
791
CMDGF
796
LQDPE
801
GNCVD
806
INECT
811
SLSEP
816
CRPGF
821
SCINT
826
VGSYT
831
CQRNP
836
LICAR
841
GYHAS
846
DDGTK
851
CVDVN
856
ECETG
861
VHRCG
866
EGQVC
871
HNLPG
876
SYRCD
881
CKAGF
886
QRDAF
891
GRGCI
896
DVNEC
901
WASPG
906
RLCQH
911
TCENT
916
LGSYR
921
CSCAS
926
GFLLA
931
ADGKR
936
CEDVN
941
ECEAQ
946
RCSQE
951
CANIY
956
GSYQC
961
YCRQG
966
YQLAE
971
DGHTC
976
TDIDE
981
CAQGA
986
GILCT
991
FRCLN
996
VPGSY
1001
QCACP
1006
EQGYT
1011
MTANG
1016
RSCKD
1021
VDECA
1026
LGTHN
1031
CSEAE
1036
TCHNI
1041
QGSFR
1046
CLRFE
1051
CPPNY
1056
VQVSK
1061
TKCER
1066
TTCHD
1071
FLECQ
1076
NSPAR
1081
ITHYQ
1086
LNFQT
1091
GLLVP
1096
AHIFR
1101
IGPAP
1106
AFTGD
1111
TIALN
1116
IIKGN
1121
EEGYF
1126
GTRRL
1131
NAYTG
1136
VVYLQ
1141
RAVLE
1146
PRDFA
1151
LDVEM
1156
KLWRQ
1161
GSVTT
1166
FLAKM
1171
HIFFT
1176
TFAL
1181
Mutation Information
DNA mutation:
None
Peptide Range:
518 ~ 542
Mut AA position:
530 (13 in Wild Type peptide)
Alignment
Wild Type:
"CCDCCGLGLRVRAEGQSCESNPNLG
||||||||||||.||||||||||||
Mutant:
CCDCCGLGLRVRVEGQSCESNPNLG"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) FBLN2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay