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1851
A
N
L
M
T
G
F
C
T
T
V
I
A
T
S
P
V
D
V
V
K
T
R
Y
M
N
Science, 2015
A
N
L
M
T
G
F
C
T
T
V
I
A
T
S
P
V
D
V
V
K
T
R
Y
M
N
C*08:02(Negative)
Gene Symbol:
UCP2
Tumor Type:
Rectal cancer
Copy WT Sequence
1852
A
N
L
M
T
G
F
C
T
T
V
I
A
T
S
P
V
D
V
V
K
T
R
Y
M
N
Science, 2015
A
N
L
M
T
G
F
C
T
T
V
I
A
T
S
P
V
D
V
V
K
T
R
Y
M
N
A*29:02(Negative)
Gene Symbol:
UCP2
Tumor Type:
Rectal cancer
Copy WT Sequence
1853
A
N
L
M
T
G
F
C
T
T
V
I
A
T
S
P
V
D
V
V
K
T
R
Y
M
N
Science, 2015
A
N
L
M
T
G
F
C
T
T
V
I
A
T
S
P
V
D
V
V
K
T
R
Y
M
N
C*16:01(Negative)
Gene Symbol:
UCP2
Tumor Type:
Rectal cancer
Copy WT Sequence
1854
D
P
D
C
V
D
R
L
L
Q
C
T
R
Q
Q
A
V
P
L
F
S
V
L
K
L
L
Science, 2015
D
P
D
C
V
D
R
L
L
Q
C
T
R
Q
Q
A
V
P
L
F
S
V
L
K
L
L
A*02:01(Negative)
Gene Symbol:
API5
Tumor Type:
Colon cancer
Copy WT Sequence
1855
D
P
D
C
V
D
R
L
L
Q
C
T
R
Q
Q
A
V
P
L
F
S
V
L
K
L
L
Science, 2015
D
P
D
C
V
D
R
L
L
Q
C
T
R
Q
Q
A
V
P
L
F
S
V
L
K
L
L
A*03:01(Negative)
Gene Symbol:
API5
Tumor Type:
Colon cancer
Copy WT Sequence
1856
D
P
D
C
V
D
R
L
L
Q
C
T
R
Q
Q
A
V
P
L
F
S
V
L
K
L
L
Science, 2015
D
P
D
C
V
D
R
L
L
Q
C
T
R
Q
Q
A
V
P
L
F
S
V
L
K
L
L
B*13:02(Negative)
Gene Symbol:
API5
Tumor Type:
Colon cancer
Copy WT Sequence
1857
D
P
D
C
V
D
R
L
L
Q
C
T
R
Q
Q
A
V
P
L
F
S
V
L
K
L
L
Science, 2015
D
P
D
C
V
D
R
L
L
Q
C
T
R
Q
Q
A
V
P
L
F
S
V
L
K
L
L
C*05:01(Negative)
Gene Symbol:
API5
Tumor Type:
Colon cancer
Copy WT Sequence
1858
D
P
D
C
V
D
R
L
L
Q
C
T
R
Q
Q
A
V
P
L
F
S
V
L
K
L
L
Science, 2015
D
P
D
C
V
D
R
L
L
Q
C
T
R
Q
Q
A
V
P
L
F
S
V
L
K
L
L
C*06:02(Negative)
Gene Symbol:
API5
Tumor Type:
Colon cancer
Copy WT Sequence
1859
D
P
D
C
V
D
R
L
L
Q
C
T
R
Q
Q
A
V
P
L
F
S
V
L
K
L
L
Science, 2015
D
P
D
C
V
D
R
L
L
Q
C
T
R
Q
Q
A
V
P
L
F
S
V
L
K
L
L
B*15:01(Negative)
Gene Symbol:
API5
Tumor Type:
Colon cancer
Copy WT Sequence
1860
A
S
D
L
K
K
L
R
E
Q
Q
E
T
M
E
R
K
E
A
A
S
R
L
R
M
A
Science, 2015
A
S
D
L
K
K
L
R
E
Q
Q
E
T
M
E
R
K
E
A
A
S
R
L
R
M
A
DRB*07:01
(Negative)
Gene Symbol:
TEX13A
Tumor Type:
Rectal cancer
Copy WT Sequence
1861
A
S
D
L
K
K
L
R
E
Q
Q
E
T
M
E
R
K
E
A
A
S
R
L
R
M
A
Science, 2015
A
S
D
L
K
K
L
R
E
Q
Q
E
T
M
E
R
K
E
A
A
S
R
L
R
M
A
DQA*02:01/DQB*02:02
(Negative)
Gene Symbol:
TEX13A
Tumor Type:
Rectal cancer
Copy WT Sequence
1862
A
S
D
L
K
K
L
R
E
Q
Q
E
T
M
E
R
K
E
A
A
S
R
L
R
M
A
Science, 2015
A
S
D
L
K
K
L
R
E
Q
Q
E
T
M
E
R
K
E
A
A
S
R
L
R
M
A
B*44:03(Negative)
Gene Symbol:
TEX13A
Tumor Type:
Rectal cancer
Copy WT Sequence
1863
A
S
D
L
K
K
L
R
E
Q
Q
E
T
M
E
R
K
E
A
A
S
R
L
R
M
A
Science, 2015
A
S
D
L
K
K
L
R
E
Q
Q
E
T
M
E
R
K
E
A
A
S
R
L
R
M
A
B*14:02(Negative)
Gene Symbol:
TEX13A
Tumor Type:
Rectal cancer
Copy WT Sequence
1864
A
S
D
L
K
K
L
R
E
Q
Q
E
T
M
E
R
K
E
A
A
S
R
L
R
M
A
Science, 2015
A
S
D
L
K
K
L
R
E
Q
Q
E
T
M
E
R
K
E
A
A
S
R
L
R
M
A
C*08:02(Negative)
Gene Symbol:
TEX13A
Tumor Type:
Rectal cancer
Copy WT Sequence
1865
A
S
D
L
K
K
L
R
E
Q
Q
E
T
M
E
R
K
E
A
A
S
R
L
R
M
A
Science, 2015
A
S
D
L
K
K
L
R
E
Q
Q
E
T
M
E
R
K
E
A
A
S
R
L
R
M
A
A*29:02(Negative)
Gene Symbol:
TEX13A
Tumor Type:
Rectal cancer
Copy WT Sequence
1866
A
S
D
L
K
K
L
R
E
Q
Q
E
T
M
E
R
K
E
A
A
S
R
L
R
M
A
Science, 2015
A
S
D
L
K
K
L
R
E
Q
Q
E
T
M
E
R
K
E
A
A
S
R
L
R
M
A
C*16:01(Negative)
Gene Symbol:
TEX13A
Tumor Type:
Rectal cancer
Copy WT Sequence
1867
C
I
N
S
I
W
W
C
D
F
D
N
D
N
C
G
D
M
S
D
E
R
N
C
P
T
Science, 2015
C
I
N
S
I
W
W
C
D
F
D
N
D
N
C
G
D
M
S
D
E
R
N
C
P
T
DQA*01:03/DQB*02:05
(Negative)
Gene Symbol:
SORL1
Tumor Type:
Colon cancer
Copy WT Sequence
1868
C
I
N
S
I
W
W
C
D
F
D
N
D
N
C
G
D
M
S
D
E
R
N
C
P
T
Science, 2015
C
I
N
S
I
W
W
C
D
F
D
N
D
N
C
G
D
M
S
D
E
R
N
C
P
T
A*02:01(Negative)
Gene Symbol:
SORL1
Tumor Type:
Colon cancer
Copy WT Sequence
1869
C
I
N
S
I
W
W
C
D
F
D
N
D
N
C
G
D
M
S
D
E
R
N
C
P
T
Science, 2015
C
I
N
S
I
W
W
C
D
F
D
N
D
N
C
G
D
M
S
D
E
R
N
C
P
T
DQA*05:01/DQB*06:03
(Negative)
Gene Symbol:
SORL1
Tumor Type:
Colon cancer
Copy WT Sequence
1870
C
I
N
S
I
W
W
C
D
F
D
N
D
N
C
G
D
M
S
D
E
R
N
C
P
T
Science, 2015
C
I
N
S
I
W
W
C
D
F
D
N
D
N
C
G
D
M
S
D
E
R
N
C
P
T
C*07:01(Negative)
Gene Symbol:
SORL1
Tumor Type:
Colon cancer
Copy WT Sequence
1871
C
I
N
S
I
W
W
C
D
F
D
N
D
N
C
G
D
M
S
D
E
R
N
C
P
T
Science, 2015
C
I
N
S
I
W
W
C
D
F
D
N
D
N
C
G
D
M
S
D
E
R
N
C
P
T
C*01:02(Negative)
Gene Symbol:
SORL1
Tumor Type:
Colon cancer
Copy WT Sequence
1872
C
I
N
S
I
W
W
C
D
F
D
N
D
N
C
G
D
M
S
D
E
R
N
C
P
T
Science, 2015
C
I
N
S
I
W
W
C
D
F
D
N
D
N
C
G
D
M
S
D
E
R
N
C
P
T
DRB*03:01
(Negative)
Gene Symbol:
SORL1
Tumor Type:
Colon cancer
Copy WT Sequence
1873
C
I
N
S
I
W
W
C
D
F
D
N
D
N
C
G
D
M
S
D
E
R
N
C
P
T
Science, 2015
C
I
N
S
I
W
W
C
D
F
D
N
D
N
C
G
D
M
S
D
E
R
N
C
P
T
DRB*13:01
(Negative)
Gene Symbol:
SORL1
Tumor Type:
Colon cancer
Copy WT Sequence
1874
C
I
N
S
I
W
W
C
D
F
D
N
D
N
C
G
D
M
S
D
E
R
N
C
P
T
Science, 2015
C
I
N
S
I
W
W
C
D
F
D
N
D
N
C
G
D
M
S
D
E
R
N
C
P
T
B*08:01(Negative)
Gene Symbol:
SORL1
Tumor Type:
Colon cancer
Copy WT Sequence
1875
C
I
N
S
I
W
W
C
D
F
D
N
D
N
C
G
D
M
S
D
E
R
N
C
P
T
Science, 2015
C
I
N
S
I
W
W
C
D
F
D
N
D
N
C
G
D
M
S
D
E
R
N
C
P
T
A*01:01(Negative)
Gene Symbol:
SORL1
Tumor Type:
Colon cancer
Copy WT Sequence
1876
C
I
N
S
I
W
W
C
D
F
D
N
D
N
C
G
D
M
S
D
E
R
N
C
P
T
Science, 2015
C
I
N
S
I
W
W
C
D
F
D
N
D
N
C
G
D
M
S
D
E
R
N
C
P
T
B*56:01(Negative)
Gene Symbol:
SORL1
Tumor Type:
Colon cancer
Copy WT Sequence
1877
R
L
V
R
G
S
V
C
A
G
K
L
F
L
I
A
P
L
I
M
V
L
G
L
A
L
Science, 2015
R
L
V
R
G
S
V
C
A
G
K
L
F
L
I
A
P
L
I
M
V
L
G
L
A
L
DRB*07:01
(Negative)
Gene Symbol:
RNF217
Tumor Type:
Rectal cancer
Copy WT Sequence
1878
R
L
V
R
G
S
V
C
A
G
K
L
F
L
I
A
P
L
I
M
V
L
G
L
A
L
Science, 2015
R
L
V
R
G
S
V
C
A
G
K
L
F
L
I
A
P
L
I
M
V
L
G
L
A
L
DQA*02:01/DQB*02:02
(Negative)
Gene Symbol:
RNF217
Tumor Type:
Rectal cancer
Copy WT Sequence
1879
R
L
V
R
G
S
V
C
A
G
K
L
F
L
I
A
P
L
I
M
V
L
G
L
A
L
Science, 2015
R
L
V
R
G
S
V
C
A
G
K
L
F
L
I
A
P
L
I
M
V
L
G
L
A
L
B*44:03(Negative)
Gene Symbol:
RNF217
Tumor Type:
Rectal cancer
Copy WT Sequence
1880
R
L
V
R
G
S
V
C
A
G
K
L
F
L
I
A
P
L
I
M
V
L
G
L
A
L
Science, 2015
R
L
V
R
G
S
V
C
A
G
K
L
F
L
I
A
P
L
I
M
V
L
G
L
A
L
B*14:02(Negative)
Gene Symbol:
RNF217
Tumor Type:
Rectal cancer
Copy WT Sequence
1881
R
L
V
R
G
S
V
C
A
G
K
L
F
L
I
A
P
L
I
M
V
L
G
L
A
L
Science, 2015
R
L
V
R
G
S
V
C
A
G
K
L
F
L
I
A
P
L
I
M
V
L
G
L
A
L
C*08:02(Negative)
Gene Symbol:
RNF217
Tumor Type:
Rectal cancer
Copy WT Sequence
1882
R
L
V
R
G
S
V
C
A
G
K
L
F
L
I
A
P
L
I
M
V
L
G
L
A
L
Science, 2015
R
L
V
R
G
S
V
C
A
G
K
L
F
L
I
A
P
L
I
M
V
L
G
L
A
L
A*29:02(Negative)
Gene Symbol:
RNF217
Tumor Type:
Rectal cancer
Copy WT Sequence
1883
R
L
V
R
G
S
V
C
A
G
K
L
F
L
I
A
P
L
I
M
V
L
G
L
A
L
Science, 2015
R
L
V
R
G
S
V
C
A
G
K
L
F
L
I
A
P
L
I
M
V
L
G
L
A
L
C*16:01(Negative)
Gene Symbol:
RNF217
Tumor Type:
Rectal cancer
Copy WT Sequence
1884
Q
A
G
A
P
A
G
R
G
L
E
D
Q
R
R
R
G
A
P
S
E
P
S
L
R
I
Science, 2015
Q
A
G
A
P
A
G
R
G
L
E
D
Q
R
R
R
G
A
P
S
E
P
S
L
R
I
DQA*01:03/DQB*02:05
(Negative)
Gene Symbol:
PCSK4
Tumor Type:
Colon cancer
Copy WT Sequence
1885
Q
A
G
A
P
A
G
R
G
L
E
D
Q
R
R
R
G
A
P
S
E
P
S
L
R
I
Science, 2015
Q
A
G
A
P
A
G
R
G
L
E
D
Q
R
R
R
G
A
P
S
E
P
S
L
R
I
A*02:01(Negative)
Gene Symbol:
PCSK4
Tumor Type:
Colon cancer
Copy WT Sequence
1886
Q
A
G
A
P
A
G
R
G
L
E
D
Q
R
R
R
G
A
P
S
E
P
S
L
R
I
Science, 2015
Q
A
G
A
P
A
G
R
G
L
E
D
Q
R
R
R
G
A
P
S
E
P
S
L
R
I
DQA*05:01/DQB*06:03
(Negative)
Gene Symbol:
PCSK4
Tumor Type:
Colon cancer
Copy WT Sequence
1887
Q
A
G
A
P
A
G
R
G
L
E
D
Q
R
R
R
G
A
P
S
E
P
S
L
R
I
Science, 2015
Q
A
G
A
P
A
G
R
G
L
E
D
Q
R
R
R
G
A
P
S
E
P
S
L
R
I
C*07:01(Negative)
Gene Symbol:
PCSK4
Tumor Type:
Colon cancer
Copy WT Sequence
1888
Q
A
G
A
P
A
G
R
G
L
E
D
Q
R
R
R
G
A
P
S
E
P
S
L
R
I
Science, 2015
Q
A
G
A
P
A
G
R
G
L
E
D
Q
R
R
R
G
A
P
S
E
P
S
L
R
I
C*01:02(Negative)
Gene Symbol:
PCSK4
Tumor Type:
Colon cancer
Copy WT Sequence
1889
Q
A
G
A
P
A
G
R
G
L
E
D
Q
R
R
R
G
A
P
S
E
P
S
L
R
I
Science, 2015
Q
A
G
A
P
A
G
R
G
L
E
D
Q
R
R
R
G
A
P
S
E
P
S
L
R
I
DRB*03:01
(Negative)
Gene Symbol:
PCSK4
Tumor Type:
Colon cancer
Copy WT Sequence
1890
Q
A
G
A
P
A
G
R
G
L
E
D
Q
R
R
R
G
A
P
S
E
P
S
L
R
I
Science, 2015
Q
A
G
A
P
A
G
R
G
L
E
D
Q
R
R
R
G
A
P
S
E
P
S
L
R
I
DRB*13:01
(Negative)
Gene Symbol:
PCSK4
Tumor Type:
Colon cancer
Copy WT Sequence
1891
Q
A
G
A
P
A
G
R
G
L
E
D
Q
R
R
R
G
A
P
S
E
P
S
L
R
I
Science, 2015
Q
A
G
A
P
A
G
R
G
L
E
D
Q
R
R
R
G
A
P
S
E
P
S
L
R
I
B*08:01(Negative)
Gene Symbol:
PCSK4
Tumor Type:
Colon cancer
Copy WT Sequence
1892
Q
A
G
A
P
A
G
R
G
L
E
D
Q
R
R
R
G
A
P
S
E
P
S
L
R
I
Science, 2015
Q
A
G
A
P
A
G
R
G
L
E
D
Q
R
R
R
G
A
P
S
E
P
S
L
R
I
A*01:01(Negative)
Gene Symbol:
PCSK4
Tumor Type:
Colon cancer
Copy WT Sequence
1893
Q
A
G
A
P
A
G
R
G
L
E
D
Q
R
R
R
G
A
P
S
E
P
S
L
R
I
Science, 2015
Q
A
G
A
P
A
G
R
G
L
E
D
Q
R
R
R
G
A
P
S
E
P
S
L
R
I
B*56:01(Negative)
Gene Symbol:
PCSK4
Tumor Type:
Colon cancer
Copy WT Sequence
1894
D
H
T
T
L
L
S
E
A
N
V
P
G
C
T
T
G
D
D
A
K
D
Science, 2015
D
H
T
T
L
L
S
E
A
N
V
P
G
C
T
T
G
D
D
A
K
D
DQA*01:02/DQB*06:02
(Negative)
Gene Symbol:
IMPDH1
Tumor Type:
Colon cancer
Copy WT Sequence
1895
D
H
T
T
L
L
S
E
A
N
V
P
G
C
T
T
G
D
D
A
K
D
Science, 2015
D
H
T
T
L
L
S
E
A
N
V
P
G
C
T
T
G
D
D
A
K
D
A*03:01(Negative)
Gene Symbol:
IMPDH1
Tumor Type:
Colon cancer
Copy WT Sequence
1896
D
H
T
T
L
L
S
E
A
N
V
P
G
C
T
T
G
D
D
A
K
D
Science, 2015
D
H
T
T
L
L
S
E
A
N
V
P
G
C
T
T
G
D
D
A
K
D
DRB*15:01
(Negative)
Gene Symbol:
IMPDH1
Tumor Type:
Colon cancer
Copy WT Sequence
1897
D
H
T
T
L
L
S
E
A
N
V
P
G
C
T
T
G
D
D
A
K
D
Science, 2015
D
H
T
T
L
L
S
E
A
N
V
P
G
C
T
T
G
D
D
A
K
D
C*07:02(Negative)
Gene Symbol:
IMPDH1
Tumor Type:
Colon cancer
Copy WT Sequence
1898
D
H
T
T
L
L
S
E
A
N
V
P
G
C
T
T
G
D
D
A
K
D
Science, 2015
D
H
T
T
L
L
S
E
A
N
V
P
G
C
T
T
G
D
D
A
K
D
B*07:02(Negative)
Gene Symbol:
IMPDH1
Tumor Type:
Colon cancer
Copy WT Sequence
1899
Y
I
Q
H
Q
R
I
Q
T
G
E
K
P
A
Y
E
C
M
E
C
G
K
A
F
G
R
Science, 2015
Y
I
Q
H
Q
R
I
Q
T
G
E
K
P
A
Y
E
C
M
E
C
G
K
A
F
G
R
DRB*07:01
(Negative)
Gene Symbol:
ZNF571
Tumor Type:
Rectal cancer
Copy WT Sequence
1900
Y
I
Q
H
Q
R
I
Q
T
G
E
K
P
A
Y
E
C
M
E
C
G
K
A
F
G
R
Science, 2015
Y
I
Q
H
Q
R
I
Q
T
G
E
K
P
A
Y
E
C
M
E
C
G
K
A
F
G
R
DQA*02:01/DQB*02:02
(Negative)
Gene Symbol:
ZNF571
Tumor Type:
Rectal cancer
Copy WT Sequence