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501
R
V
T
M
S
V
D
T
S
K
N
Q
F
L
S
L
K
L
S
S
V
T
A
V
D
T
Science, 2015
R
V
T
M
S
V
D
T
S
K
N
Q
F
L
S
L
K
L
S
S
V
T
A
V
D
T
DQA*05:01/DQB*02:02
(Negative)
Gene Symbol:
IGHV4-28
Tumor Type:
Colon cancer
Copy WT Sequence
502
R
V
T
M
S
V
D
T
S
K
N
Q
F
L
S
L
K
L
S
S
V
T
A
V
D
T
Science, 2015
R
V
T
M
S
V
D
T
S
K
N
Q
F
L
S
L
K
L
S
S
V
T
A
V
D
T
B*18:01(Negative)
Gene Symbol:
IGHV4-28
Tumor Type:
Colon cancer
Copy WT Sequence
503
R
V
T
M
S
V
D
T
S
K
N
Q
F
L
S
L
K
L
S
S
V
T
A
V
D
T
Science, 2015
R
V
T
M
S
V
D
T
S
K
N
Q
F
L
S
L
K
L
S
S
V
T
A
V
D
T
A*30:02(Negative)
Gene Symbol:
IGHV4-28
Tumor Type:
Colon cancer
Copy WT Sequence
504
K
N
S
L
Y
L
Q
M
N
S
L
R
D
A
E
D
T
A
V
Y
Y
C
A
R
Science, 2015
K
N
S
L
Y
L
Q
M
N
S
L
R
D
A
E
D
T
A
V
Y
Y
C
A
R
C*12:02(Negative)
Gene Symbol:
IGHV3-48
Tumor Type:
Pancreatic cancer
Copy WT Sequence
505
K
N
S
L
Y
L
Q
M
N
S
L
R
D
A
E
D
T
A
V
Y
Y
C
A
R
Science, 2015
K
N
S
L
Y
L
Q
M
N
S
L
R
D
A
E
D
T
A
V
Y
Y
C
A
R
B*52:01(Negative)
Gene Symbol:
IGHV3-48
Tumor Type:
Pancreatic cancer
Copy WT Sequence
506
K
N
S
L
Y
L
Q
M
N
S
L
R
D
A
E
D
T
A
V
Y
Y
C
A
R
Science, 2015
K
N
S
L
Y
L
Q
M
N
S
L
R
D
A
E
D
T
A
V
Y
Y
C
A
R
C*12:03(Negative)
Gene Symbol:
IGHV3-48
Tumor Type:
Pancreatic cancer
Copy WT Sequence
507
K
N
S
L
Y
L
Q
M
N
S
L
R
D
A
E
D
T
A
V
Y
Y
C
A
R
Science, 2015
K
N
S
L
Y
L
Q
M
N
S
L
R
D
A
E
D
T
A
V
Y
Y
C
A
R
A*11:01(Negative)
Gene Symbol:
IGHV3-48
Tumor Type:
Pancreatic cancer
Copy WT Sequence
508
K
N
S
L
Y
L
Q
M
N
S
L
R
D
A
E
D
T
A
V
Y
Y
C
A
R
Science, 2015
K
N
S
L
Y
L
Q
M
N
S
L
R
D
A
E
D
T
A
V
Y
Y
C
A
R
DQA*01:03/DQB*03:02
(Negative)
Gene Symbol:
IGHV3-48
Tumor Type:
Pancreatic cancer
Copy WT Sequence
509
K
N
S
L
Y
L
Q
M
N
S
L
R
D
A
E
D
T
A
V
Y
Y
C
A
R
Science, 2015
K
N
S
L
Y
L
Q
M
N
S
L
R
D
A
E
D
T
A
V
Y
Y
C
A
R
DQA*03:01/DQB*06:01
(Negative)
Gene Symbol:
IGHV3-48
Tumor Type:
Pancreatic cancer
Copy WT Sequence
510
K
N
S
L
Y
L
Q
M
N
S
L
R
D
A
E
D
T
A
V
Y
Y
C
A
R
Science, 2015
K
N
S
L
Y
L
Q
M
N
S
L
R
D
A
E
D
T
A
V
Y
Y
C
A
R
DRB*15:02
(Negative)
Gene Symbol:
IGHV3-48
Tumor Type:
Pancreatic cancer
Copy WT Sequence
511
K
N
S
L
Y
L
Q
M
N
S
L
R
D
A
E
D
T
A
V
Y
Y
C
A
R
Science, 2015
K
N
S
L
Y
L
Q
M
N
S
L
R
D
A
E
D
T
A
V
Y
Y
C
A
R
DRB*04:02
(Negative)
Gene Symbol:
IGHV3-48
Tumor Type:
Pancreatic cancer
Copy WT Sequence
512
K
N
S
L
Y
L
Q
M
N
S
L
R
D
A
E
D
T
A
V
Y
Y
C
A
R
Science, 2015
K
N
S
L
Y
L
Q
M
N
S
L
R
D
A
E
D
T
A
V
Y
Y
C
A
R
A*26:01(Negative)
Gene Symbol:
IGHV3-48
Tumor Type:
Pancreatic cancer
Copy WT Sequence
513
K
N
S
L
Y
L
Q
M
N
S
L
R
D
A
E
D
T
A
V
Y
Y
C
A
R
Science, 2015
K
N
S
L
Y
L
Q
M
N
S
L
R
D
A
E
D
T
A
V
Y
Y
C
A
R
B*38:01(Negative)
Gene Symbol:
IGHV3-48
Tumor Type:
Pancreatic cancer
Copy WT Sequence
514
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
Science, 2015
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
B*14:01(Negative)
Gene Symbol:
IGHV3-53
Tumor Type:
Colon cancer
Copy WT Sequence
515
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
Science, 2015
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
DRB*07:01
(Negative)
Gene Symbol:
IGHV3-53
Tumor Type:
Colon cancer
Copy WT Sequence
516
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
Science, 2015
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
A*32:01(Negative)
Gene Symbol:
IGHV3-53
Tumor Type:
Colon cancer
Copy WT Sequence
517
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
Science, 2015
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
C*05:01(Negative)
Gene Symbol:
IGHV3-53
Tumor Type:
Colon cancer
Copy WT Sequence
518
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
Science, 2015
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
DRB*03:01
(Negative)
Gene Symbol:
IGHV3-53
Tumor Type:
Colon cancer
Copy WT Sequence
519
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
Science, 2015
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
DQA*02:01/DQB*02:01
(Negative)
Gene Symbol:
IGHV3-53
Tumor Type:
Colon cancer
Copy WT Sequence
520
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
Science, 2015
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
C*08:02(Negative)
Gene Symbol:
IGHV3-53
Tumor Type:
Colon cancer
Copy WT Sequence
521
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
Science, 2015
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
DQA*05:01/DQB*02:02
(Negative)
Gene Symbol:
IGHV3-53
Tumor Type:
Colon cancer
Copy WT Sequence
522
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
Science, 2015
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
B*18:01(Negative)
Gene Symbol:
IGHV3-53
Tumor Type:
Colon cancer
Copy WT Sequence
523
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
Science, 2015
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
A*30:02(Negative)
Gene Symbol:
IGHV3-53
Tumor Type:
Colon cancer
Copy WT Sequence
524
M
E
F
W
L
S
W
V
L
L
V
A
I
V
L
K
G
V
Q
C
E
V
Q
L
V
E
Science, 2015
M
E
F
W
L
S
W
V
L
L
V
A
I
V
L
K
G
V
Q
C
E
V
Q
L
V
E
B*14:01(Negative)
Gene Symbol:
IGHV3-53
Tumor Type:
Colon cancer
Copy WT Sequence
525
M
E
F
W
L
S
W
V
L
L
V
A
I
V
L
K
G
V
Q
C
E
V
Q
L
V
E
Science, 2015
M
E
F
W
L
S
W
V
L
L
V
A
I
V
L
K
G
V
Q
C
E
V
Q
L
V
E
DRB*07:01
(Negative)
Gene Symbol:
IGHV3-53
Tumor Type:
Colon cancer
Copy WT Sequence
526
M
E
F
W
L
S
W
V
L
L
V
A
I
V
L
K
G
V
Q
C
E
V
Q
L
V
E
Science, 2015
M
E
F
W
L
S
W
V
L
L
V
A
I
V
L
K
G
V
Q
C
E
V
Q
L
V
E
A*32:01(Negative)
Gene Symbol:
IGHV3-53
Tumor Type:
Colon cancer
Copy WT Sequence
527
M
E
F
W
L
S
W
V
L
L
V
A
I
V
L
K
G
V
Q
C
E
V
Q
L
V
E
Science, 2015
M
E
F
W
L
S
W
V
L
L
V
A
I
V
L
K
G
V
Q
C
E
V
Q
L
V
E
C*05:01(Negative)
Gene Symbol:
IGHV3-53
Tumor Type:
Colon cancer
Copy WT Sequence
528
M
E
F
W
L
S
W
V
L
L
V
A
I
V
L
K
G
V
Q
C
E
V
Q
L
V
E
Science, 2015
M
E
F
W
L
S
W
V
L
L
V
A
I
V
L
K
G
V
Q
C
E
V
Q
L
V
E
DRB*03:01
(Negative)
Gene Symbol:
IGHV3-53
Tumor Type:
Colon cancer
Copy WT Sequence
529
M
E
F
W
L
S
W
V
L
L
V
A
I
V
L
K
G
V
Q
C
E
V
Q
L
V
E
Science, 2015
M
E
F
W
L
S
W
V
L
L
V
A
I
V
L
K
G
V
Q
C
E
V
Q
L
V
E
DQA*02:01/DQB*02:01
(Negative)
Gene Symbol:
IGHV3-53
Tumor Type:
Colon cancer
Copy WT Sequence
530
M
E
F
W
L
S
W
V
L
L
V
A
I
V
L
K
G
V
Q
C
E
V
Q
L
V
E
Science, 2015
M
E
F
W
L
S
W
V
L
L
V
A
I
V
L
K
G
V
Q
C
E
V
Q
L
V
E
C*08:02(Negative)
Gene Symbol:
IGHV3-53
Tumor Type:
Colon cancer
Copy WT Sequence
531
M
E
F
W
L
S
W
V
L
L
V
A
I
V
L
K
G
V
Q
C
E
V
Q
L
V
E
Science, 2015
M
E
F
W
L
S
W
V
L
L
V
A
I
V
L
K
G
V
Q
C
E
V
Q
L
V
E
DQA*05:01/DQB*02:02
(Negative)
Gene Symbol:
IGHV3-53
Tumor Type:
Colon cancer
Copy WT Sequence
532
M
E
F
W
L
S
W
V
L
L
V
A
I
V
L
K
G
V
Q
C
E
V
Q
L
V
E
Science, 2015
M
E
F
W
L
S
W
V
L
L
V
A
I
V
L
K
G
V
Q
C
E
V
Q
L
V
E
B*18:01(Negative)
Gene Symbol:
IGHV3-53
Tumor Type:
Colon cancer
Copy WT Sequence
533
M
E
F
W
L
S
W
V
L
L
V
A
I
V
L
K
G
V
Q
C
E
V
Q
L
V
E
Science, 2015
M
E
F
W
L
S
W
V
L
L
V
A
I
V
L
K
G
V
Q
C
E
V
Q
L
V
E
A*30:02(Negative)
Gene Symbol:
IGHV3-53
Tumor Type:
Colon cancer
Copy WT Sequence
534
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
Science, 2015
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
A*02:01(Negative)
Gene Symbol:
IGHV4-59
Tumor Type:
Colon cancer
Copy WT Sequence
535
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
Science, 2015
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
A*03:01(Negative)
Gene Symbol:
IGHV4-59
Tumor Type:
Colon cancer
Copy WT Sequence
536
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
Science, 2015
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
B*13:02(Negative)
Gene Symbol:
IGHV4-59
Tumor Type:
Colon cancer
Copy WT Sequence
537
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
Science, 2015
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
C*05:01(Negative)
Gene Symbol:
IGHV4-59
Tumor Type:
Colon cancer
Copy WT Sequence
538
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
Science, 2015
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
C*06:02(Negative)
Gene Symbol:
IGHV4-59
Tumor Type:
Colon cancer
Copy WT Sequence
539
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
Science, 2015
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
B*15:01(Negative)
Gene Symbol:
IGHV4-59
Tumor Type:
Colon cancer
Copy WT Sequence
540
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
Science, 2015
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
B*14:01(Negative)
Gene Symbol:
IGHV4-61
Tumor Type:
Colon cancer
Copy WT Sequence
541
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
Science, 2015
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
DRB*07:01
(Negative)
Gene Symbol:
IGHV4-61
Tumor Type:
Colon cancer
Copy WT Sequence
542
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
Science, 2015
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
A*32:01(Negative)
Gene Symbol:
IGHV4-61
Tumor Type:
Colon cancer
Copy WT Sequence
543
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
Science, 2015
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
C*05:01(Negative)
Gene Symbol:
IGHV4-61
Tumor Type:
Colon cancer
Copy WT Sequence
544
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
Science, 2015
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
DRB*03:01
(Negative)
Gene Symbol:
IGHV4-61
Tumor Type:
Colon cancer
Copy WT Sequence
545
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
Science, 2015
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
DQA*02:01/DQB*02:01
(Negative)
Gene Symbol:
IGHV4-61
Tumor Type:
Colon cancer
Copy WT Sequence
546
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
Science, 2015
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
C*08:02(Negative)
Gene Symbol:
IGHV4-61
Tumor Type:
Colon cancer
Copy WT Sequence
547
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
Science, 2015
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
DQA*05:01/DQB*02:02
(Negative)
Gene Symbol:
IGHV4-61
Tumor Type:
Colon cancer
Copy WT Sequence
548
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
Science, 2015
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
B*18:01(Negative)
Gene Symbol:
IGHV4-61
Tumor Type:
Colon cancer
Copy WT Sequence
549
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
Science, 2015
W
V
L
S
Q
V
Q
L
Q
E
S
G
P
S
G
L
V
K
P
S
E
T
L
S
L
T
A*30:02(Negative)
Gene Symbol:
IGHV4-61
Tumor Type:
Colon cancer
Copy WT Sequence
550
G
K
G
L
E
W
V
S
V
I
Y
S
C
G
G
S
T
Y
Y
A
D
S
V
K
G
R
Science, 2015
G
K
G
L
E
W
V
S
V
I
Y
S
C
G
G
S
T
Y
Y
A
D
S
V
K
G
R
DQA*01:02/DQB*06:02
(Negative)
Gene Symbol:
IGHV3-66
Tumor Type:
Colon cancer
Copy WT Sequence
551
G
K
G
L
E
W
V
S
V
I
Y
S
C
G
G
S
T
Y
Y
A
D
S
V
K
G
R
Science, 2015
G
K
G
L
E
W
V
S
V
I
Y
S
C
G
G
S
T
Y
Y
A
D
S
V
K
G
R
A*03:01(Negative)
Gene Symbol:
IGHV3-66
Tumor Type:
Colon cancer
Copy WT Sequence
552
G
K
G
L
E
W
V
S
V
I
Y
S
C
G
G
S
T
Y
Y
A
D
S
V
K
G
R
Science, 2015
G
K
G
L
E
W
V
S
V
I
Y
S
C
G
G
S
T
Y
Y
A
D
S
V
K
G
R
DRB*15:01
(Negative)
Gene Symbol:
IGHV3-66
Tumor Type:
Colon cancer
Copy WT Sequence
553
G
K
G
L
E
W
V
S
V
I
Y
S
C
G
G
S
T
Y
Y
A
D
S
V
K
G
R
Science, 2015
G
K
G
L
E
W
V
S
V
I
Y
S
C
G
G
S
T
Y
Y
A
D
S
V
K
G
R
C*07:02(Negative)
Gene Symbol:
IGHV3-66
Tumor Type:
Colon cancer
Copy WT Sequence
554
G
K
G
L
E
W
V
S
V
I
Y
S
C
G
G
S
T
Y
Y
A
D
S
V
K
G
R
Science, 2015
G
K
G
L
E
W
V
S
V
I
Y
S
C
G
G
S
T
Y
Y
A
D
S
V
K
G
R
B*07:02(Negative)
Gene Symbol:
IGHV3-66
Tumor Type:
Colon cancer
Copy WT Sequence
555
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
Science, 2015
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
A*02:01(Negative)
Gene Symbol:
IGHV3-66
Tumor Type:
Colon cancer
Copy WT Sequence
556
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
Science, 2015
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
A*03:01(Negative)
Gene Symbol:
IGHV3-66
Tumor Type:
Colon cancer
Copy WT Sequence
557
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
Science, 2015
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
B*13:02(Negative)
Gene Symbol:
IGHV3-66
Tumor Type:
Colon cancer
Copy WT Sequence
558
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
Science, 2015
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
C*05:01(Negative)
Gene Symbol:
IGHV3-66
Tumor Type:
Colon cancer
Copy WT Sequence
559
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
Science, 2015
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
C*06:02(Negative)
Gene Symbol:
IGHV3-66
Tumor Type:
Colon cancer
Copy WT Sequence
560
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
Science, 2015
C
E
V
Q
L
V
E
S
G
G
G
L
I
V
Q
P
G
G
S
L
R
L
S
C
A
A
B*15:01(Negative)
Gene Symbol:
IGHV3-66
Tumor Type:
Colon cancer
Copy WT Sequence
561
G
Q
A
P
R
L
L
I
Y
G
A
S
T
I
R
A
T
G
I
P
A
R
F
S
G
S
Science, 2015
G
Q
A
P
R
L
L
I
Y
G
A
S
T
I
R
A
T
G
I
P
A
R
F
S
G
S
B*14:01(Negative)
Gene Symbol:
IGKV3D-15
Tumor Type:
Colon cancer
Copy WT Sequence
562
G
Q
A
P
R
L
L
I
Y
G
A
S
T
I
R
A
T
G
I
P
A
R
F
S
G
S
Science, 2015
G
Q
A
P
R
L
L
I
Y
G
A
S
T
I
R
A
T
G
I
P
A
R
F
S
G
S
DRB*07:01
(Negative)
Gene Symbol:
IGKV3D-15
Tumor Type:
Colon cancer
Copy WT Sequence
563
G
Q
A
P
R
L
L
I
Y
G
A
S
T
I
R
A
T
G
I
P
A
R
F
S
G
S
Science, 2015
G
Q
A
P
R
L
L
I
Y
G
A
S
T
I
R
A
T
G
I
P
A
R
F
S
G
S
A*32:01(Negative)
Gene Symbol:
IGKV3D-15
Tumor Type:
Colon cancer
Copy WT Sequence
564
G
Q
A
P
R
L
L
I
Y
G
A
S
T
I
R
A
T
G
I
P
A
R
F
S
G
S
Science, 2015
G
Q
A
P
R
L
L
I
Y
G
A
S
T
I
R
A
T
G
I
P
A
R
F
S
G
S
C*05:01(Negative)
Gene Symbol:
IGKV3D-15
Tumor Type:
Colon cancer
Copy WT Sequence
565
G
Q
A
P
R
L
L
I
Y
G
A
S
T
I
R
A
T
G
I
P
A
R
F
S
G
S
Science, 2015
G
Q
A
P
R
L
L
I
Y
G
A
S
T
I
R
A
T
G
I
P
A
R
F
S
G
S
DRB*03:01
(Negative)
Gene Symbol:
IGKV3D-15
Tumor Type:
Colon cancer
Copy WT Sequence
566
G
Q
A
P
R
L
L
I
Y
G
A
S
T
I
R
A
T
G
I
P
A
R
F
S
G
S
Science, 2015
G
Q
A
P
R
L
L
I
Y
G
A
S
T
I
R
A
T
G
I
P
A
R
F
S
G
S
DQA*02:01/DQB*02:01
(Negative)
Gene Symbol:
IGKV3D-15
Tumor Type:
Colon cancer
Copy WT Sequence
567
G
Q
A
P
R
L
L
I
Y
G
A
S
T
I
R
A
T
G
I
P
A
R
F
S
G
S
Science, 2015
G
Q
A
P
R
L
L
I
Y
G
A
S
T
I
R
A
T
G
I
P
A
R
F
S
G
S
C*08:02(Negative)
Gene Symbol:
IGKV3D-15
Tumor Type:
Colon cancer
Copy WT Sequence
568
G
Q
A
P
R
L
L
I
Y
G
A
S
T
I
R
A
T
G
I
P
A
R
F
S
G
S
Science, 2015
G
Q
A
P
R
L
L
I
Y
G
A
S
T
I
R
A
T
G
I
P
A
R
F
S
G
S
DQA*05:01/DQB*02:02
(Negative)
Gene Symbol:
IGKV3D-15
Tumor Type:
Colon cancer
Copy WT Sequence
569
G
Q
A
P
R
L
L
I
Y
G
A
S
T
I
R
A
T
G
I
P
A
R
F
S
G
S
Science, 2015
G
Q
A
P
R
L
L
I
Y
G
A
S
T
I
R
A
T
G
I
P
A
R
F
S
G
S
B*18:01(Negative)
Gene Symbol:
IGKV3D-15
Tumor Type:
Colon cancer
Copy WT Sequence
570
G
Q
A
P
R
L
L
I
Y
G
A
S
T
I
R
A
T
G
I
P
A
R
F
S
G
S
Science, 2015
G
Q
A
P
R
L
L
I
Y
G
A
S
T
I
R
A
T
G
I
P
A
R
F
S
G
S
A*30:02(Negative)
Gene Symbol:
IGKV3D-15
Tumor Type:
Colon cancer
Copy WT Sequence
571
M
G
S
K
R
G
D
I
S
S
R
H
H
S
L
S
S
Y
E
Science, 2015
M
G
S
K
R
G
D
I
S
S
R
H
H
S
L
S
S
Y
E
DQA*01:03/DQB*02:05
(Negative)
Gene Symbol:
TMPRSS15
Tumor Type:
Colon cancer
Copy WT Sequence
572
M
G
S
K
R
G
D
I
S
S
R
H
H
S
L
S
S
Y
E
Science, 2015
M
G
S
K
R
G
D
I
S
S
R
H
H
S
L
S
S
Y
E
A*02:01(Negative)
Gene Symbol:
TMPRSS15
Tumor Type:
Colon cancer
Copy WT Sequence
573
M
G
S
K
R
G
D
I
S
S
R
H
H
S
L
S
S
Y
E
Science, 2015
M
G
S
K
R
G
D
I
S
S
R
H
H
S
L
S
S
Y
E
DQA*05:01/DQB*06:03
(Negative)
Gene Symbol:
TMPRSS15
Tumor Type:
Colon cancer
Copy WT Sequence
574
M
G
S
K
R
G
D
I
S
S
R
H
H
S
L
S
S
Y
E
Science, 2015
M
G
S
K
R
G
D
I
S
S
R
H
H
S
L
S
S
Y
E
C*07:01(Negative)
Gene Symbol:
TMPRSS15
Tumor Type:
Colon cancer
Copy WT Sequence
575
M
G
S
K
R
G
D
I
S
S
R
H
H
S
L
S
S
Y
E
Science, 2015
M
G
S
K
R
G
D
I
S
S
R
H
H
S
L
S
S
Y
E
C*01:02(Negative)
Gene Symbol:
TMPRSS15
Tumor Type:
Colon cancer
Copy WT Sequence
576
M
G
S
K
R
G
D
I
S
S
R
H
H
S
L
S
S
Y
E
Science, 2015
M
G
S
K
R
G
D
I
S
S
R
H
H
S
L
S
S
Y
E
DRB*03:01
(Negative)
Gene Symbol:
TMPRSS15
Tumor Type:
Colon cancer
Copy WT Sequence
577
M
G
S
K
R
G
D
I
S
S
R
H
H
S
L
S
S
Y
E
Science, 2015
M
G
S
K
R
G
D
I
S
S
R
H
H
S
L
S
S
Y
E
DRB*13:01
(Negative)
Gene Symbol:
TMPRSS15
Tumor Type:
Colon cancer
Copy WT Sequence
578
M
G
S
K
R
G
D
I
S
S
R
H
H
S
L
S
S
Y
E
Science, 2015
M
G
S
K
R
G
D
I
S
S
R
H
H
S
L
S
S
Y
E
B*08:01(Negative)
Gene Symbol:
TMPRSS15
Tumor Type:
Colon cancer
Copy WT Sequence
579
M
G
S
K
R
G
D
I
S
S
R
H
H
S
L
S
S
Y
E
Science, 2015
M
G
S
K
R
G
D
I
S
S
R
H
H
S
L
S
S
Y
E
A*01:01(Negative)
Gene Symbol:
TMPRSS15
Tumor Type:
Colon cancer
Copy WT Sequence
580
M
G
S
K
R
G
D
I
S
S
R
H
H
S
L
S
S
Y
E
Science, 2015
M
G
S
K
R
G
D
I
S
S
R
H
H
S
L
S
S
Y
E
B*56:01(Negative)
Gene Symbol:
TMPRSS15
Tumor Type:
Colon cancer
Copy WT Sequence
581
A
G
E
E
E
D
A
G
G
E
D
A
G
R
A
A
R
E
D
A
G
A
G
G
D
D
Science, 2015
A
G
E
E
E
D
A
G
G
E
D
A
G
R
A
A
R
E
D
A
G
A
G
G
D
D
DQA*01:02/DQB*06:02
(Negative)
Gene Symbol:
GOLGA6L2
Tumor Type:
Colon cancer
Copy WT Sequence
582
A
G
E
E
E
D
A
G
G
E
D
A
G
R
A
A
R
E
D
A
G
A
G
G
D
D
Science, 2015
A
G
E
E
E
D
A
G
G
E
D
A
G
R
A
A
R
E
D
A
G
A
G
G
D
D
A*03:01(Negative)
Gene Symbol:
GOLGA6L2
Tumor Type:
Colon cancer
Copy WT Sequence
583
A
G
E
E
E
D
A
G
G
E
D
A
G
R
A
A
R
E
D
A
G
A
G
G
D
D
Science, 2015
A
G
E
E
E
D
A
G
G
E
D
A
G
R
A
A
R
E
D
A
G
A
G
G
D
D
DRB*15:01
(Negative)
Gene Symbol:
GOLGA6L2
Tumor Type:
Colon cancer
Copy WT Sequence
584
A
G
E
E
E
D
A
G
G
E
D
A
G
R
A
A
R
E
D
A
G
A
G
G
D
D
Science, 2015
A
G
E
E
E
D
A
G
G
E
D
A
G
R
A
A
R
E
D
A
G
A
G
G
D
D
C*07:02(Negative)
Gene Symbol:
GOLGA6L2
Tumor Type:
Colon cancer
Copy WT Sequence
585
A
G
E
E
E
D
A
G
G
E
D
A
G
R
A
A
R
E
D
A
G
A
G
G
D
D
Science, 2015
A
G
E
E
E
D
A
G
G
E
D
A
G
R
A
A
R
E
D
A
G
A
G
G
D
D
B*07:02(Negative)
Gene Symbol:
GOLGA6L2
Tumor Type:
Colon cancer
Copy WT Sequence
586
A
G
G
E
D
A
G
A
G
G
E
D
A
V
G
P
G
G
E
D
A
G
A
G
G
E
Science, 2015
A
G
G
E
D
A
G
A
G
G
E
D
A
V
G
P
G
G
E
D
A
G
A
G
G
E
B*14:01(Negative)
Gene Symbol:
GOLGA6L2
Tumor Type:
Colon cancer
Copy WT Sequence
587
A
G
G
E
D
A
G
A
G
G
E
D
A
V
G
P
G
G
E
D
A
G
A
G
G
E
Science, 2015
A
G
G
E
D
A
G
A
G
G
E
D
A
V
G
P
G
G
E
D
A
G
A
G
G
E
DRB*07:01
(Negative)
Gene Symbol:
GOLGA6L2
Tumor Type:
Colon cancer
Copy WT Sequence
588
A
G
G
E
D
A
G
A
G
G
E
D
A
V
G
P
G
G
E
D
A
G
A
G
G
E
Science, 2015
A
G
G
E
D
A
G
A
G
G
E
D
A
V
G
P
G
G
E
D
A
G
A
G
G
E
A*32:01(Negative)
Gene Symbol:
GOLGA6L2
Tumor Type:
Colon cancer
Copy WT Sequence
589
A
G
G
E
D
A
G
A
G
G
E
D
A
V
G
P
G
G
E
D
A
G
A
G
G
E
Science, 2015
A
G
G
E
D
A
G
A
G
G
E
D
A
V
G
P
G
G
E
D
A
G
A
G
G
E
C*05:01(Negative)
Gene Symbol:
GOLGA6L2
Tumor Type:
Colon cancer
Copy WT Sequence
590
A
G
G
E
D
A
G
A
G
G
E
D
A
V
G
P
G
G
E
D
A
G
A
G
G
E
Science, 2015
A
G
G
E
D
A
G
A
G
G
E
D
A
V
G
P
G
G
E
D
A
G
A
G
G
E
DRB*03:01
(Negative)
Gene Symbol:
GOLGA6L2
Tumor Type:
Colon cancer
Copy WT Sequence
591
A
G
G
E
D
A
G
A
G
G
E
D
A
V
G
P
G
G
E
D
A
G
A
G
G
E
Science, 2015
A
G
G
E
D
A
G
A
G
G
E
D
A
V
G
P
G
G
E
D
A
G
A
G
G
E
DQA*02:01/DQB*02:01
(Negative)
Gene Symbol:
GOLGA6L2
Tumor Type:
Colon cancer
Copy WT Sequence
592
A
G
G
E
D
A
G
A
G
G
E
D
A
V
G
P
G
G
E
D
A
G
A
G
G
E
Science, 2015
A
G
G
E
D
A
G
A
G
G
E
D
A
V
G
P
G
G
E
D
A
G
A
G
G
E
C*08:02(Negative)
Gene Symbol:
GOLGA6L2
Tumor Type:
Colon cancer
Copy WT Sequence
593
A
G
G
E
D
A
G
A
G
G
E
D
A
V
G
P
G
G
E
D
A
G
A
G
G
E
Science, 2015
A
G
G
E
D
A
G
A
G
G
E
D
A
V
G
P
G
G
E
D
A
G
A
G
G
E
DQA*05:01/DQB*02:02
(Negative)
Gene Symbol:
GOLGA6L2
Tumor Type:
Colon cancer
Copy WT Sequence
594
A
G
G
E
D
A
G
A
G
G
E
D
A
V
G
P
G
G
E
D
A
G
A
G
G
E
Science, 2015
A
G
G
E
D
A
G
A
G
G
E
D
A
V
G
P
G
G
E
D
A
G
A
G
G
E
B*18:01(Negative)
Gene Symbol:
GOLGA6L2
Tumor Type:
Colon cancer
Copy WT Sequence
595
A
G
G
E
D
A
G
A
G
G
E
D
A
V
G
P
G
G
E
D
A
G
A
G
G
E
Science, 2015
A
G
G
E
D
A
G
A
G
G
E
D
A
V
G
P
G
G
E
D
A
G
A
G
G
E
A*30:02(Negative)
Gene Symbol:
GOLGA6L2
Tumor Type:
Colon cancer
Copy WT Sequence
596
G
N
T
R
R
C
R
S
R
R
S
G
A
G
E
D
V
G
P
E
G
E
D
V
G
A
G
R
E
Science, 2015
G
N
T
R
R
C
R
S
R
R
S
G
A
G
E
D
V
G
P
E
G
E
D
V
G
A
G
R
E
B*14:01(Negative)
Gene Symbol:
GOLGA6L2
Tumor Type:
Colon cancer
Copy WT Sequence
597
G
N
T
R
R
C
R
S
R
R
S
G
A
G
E
D
V
G
P
E
G
E
D
V
G
A
G
R
E
Science, 2015
G
N
T
R
R
C
R
S
R
R
S
G
A
G
E
D
V
G
P
E
G
E
D
V
G
A
G
R
E
DRB*07:01
(Negative)
Gene Symbol:
GOLGA6L2
Tumor Type:
Colon cancer
Copy WT Sequence
598
G
N
T
R
R
C
R
S
R
R
S
G
A
G
E
D
V
G
P
E
G
E
D
V
G
A
G
R
E
Science, 2015
G
N
T
R
R
C
R
S
R
R
S
G
A
G
E
D
V
G
P
E
G
E
D
V
G
A
G
R
E
A*32:01(Negative)
Gene Symbol:
GOLGA6L2
Tumor Type:
Colon cancer
Copy WT Sequence
599
G
N
T
R
R
C
R
S
R
R
S
G
A
G
E
D
V
G
P
E
G
E
D
V
G
A
G
R
E
Science, 2015
G
N
T
R
R
C
R
S
R
R
S
G
A
G
E
D
V
G
P
E
G
E
D
V
G
A
G
R
E
C*05:01(Negative)
Gene Symbol:
GOLGA6L2
Tumor Type:
Colon cancer
Copy WT Sequence
600
G
N
T
R
R
C
R
S
R
R
S
G
A
G
E
D
V
G
P
E
G
E
D
V
G
A
G
R
E
Science, 2015
G
N
T
R
R
C
R
S
R
R
S
G
A
G
E
D
V
G
P
E
G
E
D
V
G
A
G
R
E
DRB*03:01
(Negative)
Gene Symbol:
GOLGA6L2
Tumor Type:
Colon cancer
Copy WT Sequence